8-Hydroxyquinoline: Key Pharmaceutical Intermediate from China Suppliers and Factory for Synthesis Applications

1. Used as a pharmaceutical intermediate, it is a raw material for the synthesis of ketoconazole, chloroiodoquinol, and chlorpheniramine, as well as an intermediate for dyes and pesticides. This product is an intermediate of halogenated quinoline anti amoebic drugs, including quinolone, chloroiodoquinol, diiodoquinoline, etc. These drugs exert anti amoebic effects by inhibiting intestinal commensal bacteria, are effective against amoebic dysentery, and have no effect on extraintestinal amoebic protozoa. According to foreign reports, this type of drug can cause subacute spinal optic neuropathy, so it has been banned in Japan and the United States. Diiodoquinol is less likely to cause this disease than chloroiodoquinol. 8-Hydroxyquinoline is also an intermediate in dyes and pesticides. Its sulfates and copper salts are excellent preservatives, disinfectants, and mold inhibitors. This product is a complexometric titration indicator for chemical analysis.

2. Used as a chelating agent and extractant for precipitation and separation of metal ions, capable of reacting with Cu+2, Be+2, Mg+2, Ca+2, Sr+2, Ba+2, Zn+2, Cd+2, Al+3, Ga+3, In+3, Tl+3, Yt+3, La+3, Pb+2, B+3, Sb+3, Cr+3, MoO2+2, Mn+2, Fe+3, Co+2, Ni+2, Pd+2, Ce+3, complexing with various metal ions. Standard for determination of heterocyclic nitrogen by organic microanalysis, organic synthesis. It is also an intermediate for dyes, pesticides, and halogenated quinoline anti amoebic drugs. Its sulfates and copper salts are excellent preservatives.

3. Adding epoxy resin adhesive can improve the bonding strength and heat aging resistance to metals (especially stainless steel), and the dosage is generally 0.5-3 parts. It is an intermediate of halogenated quinoline anti amoebic drugs, as well as an intermediate of pesticides and dyes. Can be used as a mold inhibitor, industrial preservative, stabilizer for polyester resin, phenolic resin, and hydrogen peroxide, or as a complexometric titration indicator for chemical analysis.

4. This product is an intermediate of halogenated quinoline drugs, as well as an intermediate of dyes and pesticides. Its sulfates and copper salts are excellent preservatives, disinfectants, and mold inhibitors. The maximum allowable content (mass fraction) in cosmetics is 0.3%. Sunscreen products and children's products under 3 years old (such as talcum powder) are prohibited, and the product label should indicate "prohibited for children under 3 years old". When treating bacterial infected skin and bacterial infectious eczema, the mass fraction of 8-hydroxyquinoline in lotion is 0.001%~0.02%. It is also used as a disinfectant, preservative, and fungicide, with strong antifungal properties. The content (mass fraction) of 8-hydroxyquinoline potassium sulfate used in skin care cream and lotion is 0.05%~0.5%.